When Natsu opens her eyes, she is surrounded by ocean. The raging waves take her to an island together with strangers Arashi, Semimaru and Botan. The island is covered by wild jungle inhabited by giant plants, ferocious animals and humongous insects. As they struggle against these new natural enemies, a woman who claims to be their guide tells them the unbelievable truth about the 7 SEEDS plan. This involved cryogenically preserving young, healthy humans so that they could survive a global disaster and thus save mankind from extinction. Natsu and the others are shocked to learn that they are the results of the 7 SEEDS project, and now these hand-picked survivors must fight for their lives.